منابع مشابه
Recent insight into the biological activities of synthetic xanthone derivatives.
Xanthones are a class of oxygen containing heterocyclic compounds with a broad range of biological activities, and they have prominent significance in the field of medicinal chemistry. Xanthone is an attractive scaffold for the design and development of new drugs due to its promising biological activities, primarily as anticancer, antimalarial, antimicrobial, anti-HIV, anticonvulsant, anticholi...
متن کاملProgress toward synthetic cells.
The complexity of even the simplest known life forms makes efforts to synthesize living cells from inanimate components seem like a daunting task. However, recent progress toward the creation of synthetic cells, ranging from simple protocells to artificial cells approaching the complexity of bacteria, suggests that the synthesis of life is now a realistic goal. Protocell research, fueled by adv...
متن کاملProgress in synthetic classification
Classification systems are designed to contain all concepts into which a given domain of knowledge, or the whole of knowledge, is organized. Concepts are represented by both verbal terms, and their notational equivalents. The latter are devised in such a way that their ordinal sequence produces a helpful arrangement of the classified items [Ranganathan 1967, section EP]. Thus, the simplest clas...
متن کاملSynthetic approaches to the polycyclic alkaloid stemofoline.
Preliminary studies of a synthetic approach to the alkaloid stemofoline 1 are reported. Stereoselective cyclisation of the ketoester 14 gave the 1-butyl-2,8-bis(methoxycarbonyl)-8-azabicyclo[3.2.1]octane 21 in which the 2-methoxycarbonyl group is in the axial position. The analogous ketones 15, 18, and 19 were also cyclised to give the 8-azabicyclo[3.2.1]octanes 22-24 with axial electron-withdr...
متن کاملThe synthetic caged garcinia xanthone cluvenone induces cell stress and apoptosis and has immune modulatory activity.
Several caged Garcinia xanthone natural products have potent bioactivity and a documented value in traditional Eastern medicine. Previous synthesis and structure activity relationship studies of these natural products resulted in the identification of the pharmacophore represented by the structure of cluvenone. In the current study, we examined the anticancer activity of cluvenone and conducted...
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ژورنال
عنوان ژورنال: Chinese Journal of Organic Chemistry
سال: 2020
ISSN: 0253-2786
DOI: 10.6023/cjoc201911007